On a card whose left and right borders add up to 6 mm, 50/50 centering means a 3.0 mm border on one side and 3.0 mm on the other, a difference of 0.0 mm. That's invisible to the eye.
Questions
Can a 50/50 card get a PSA 10?
Yes, on centering. 50/50 is inside PSA's 55/45 front limit for a Gem Mint 10, so corners, edges and surface decide the grade.
Is 50/50 good centering?
50/50 is perfect centering. It meets every grading company's top standard, including the 50/50 that BGS and CGC require for Pristine.